NASA and its international partners are preparing to receive a significant payload of scientific research samples and hardware as a SpaceX Dragon spacecraft is scheduled to undock from the International Space Station (ISS) and return to Earth on Thursday, February 26. The departure marks the conclusion of NASA’s 33rd SpaceX Commercial Resupply Services mission.
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Live coverage of the undocking and departure will be available beginning at 11:45 a.m. EST on NASA+, Amazon Prime, and the agency’s YouTube channel. The Dragon spacecraft is programmed to autonomously undock from the ISS’s Harmony module at 12:05 p.m., subsequently firing its thrusters to maneuver safely away from the orbiting laboratory. Splashdown is anticipated later that evening, around 11:44 p.m. PST, off the coast of California. While NASA will not be streaming the splashdown event, updates will be provided on its space station blog.
The returning Dragon spacecraft carries a variety of scientific investigations that hold the potential to advance future space exploration and offer benefits for life on Earth. Among these is the Euro Material Ageing study, which spent a year in space examining the degradation of coatings, insulation, and 3D-printed materials. The findings from this experiment, along with Thailand’s Liquid Crystals investigation that observed the stability of films used in electronics in microgravity, could contribute to the development of more durable spacecraft, enhanced display technologies, and improved optical devices for future missions.
Further returning experiments include frozen samples from the Stellar Stem Cells Mission 2, aimed at understanding how microgravity impacts the growth of brain and heart stem cells, which may lead to improved treatments for neurodegenerative diseases like ALS and Parkinson’s. The SpaceDuino project, which successfully measured vibrations using a commercially available single-board computer and open-source software, is paving the way for the creation of more cost-effective instruments. Additionally, the Moon Microscope successfully tested a portable diagnostic kit designed for blood analysis in space, a crucial development for supporting future crewed missions to the Moon and Mars.
The SpaceX Dragon spacecraft supporting this mission also demonstrated a new capability to reboost the space station, a vital function for maintaining its altitude and counteracting atmospheric drag. This reboost capability is essential for the safe operations and long-term sustainability of the ISS. During its tenure docked to the station, the Dragon performed a total of six reboosts, with five occurring in 2025 and a final maneuver on January 23, prior to the preparations for its departure.
The spacecraft, laden with thousands of pounds of essential crew supplies, scientific experiments, and equipment, originally arrived at the ISS on August 25, 2025, following its launch a day prior on a Falcon 9 rocket from Cape Canaveral Space Force Station in Florida.
The International Space Station has been continuously inhabited for over 25 years, serving as a platform for advancing scientific knowledge and achieving research breakthroughs not possible on Earth. It remains a critical testbed for NASA to understand and address the challenges of long-duration spaceflight and to foster the growth of commercial opportunities in low Earth orbit. As commercial entities increasingly focus on providing human space transportation services and developing new destinations, NASA is redirecting its resources towards deep space exploration, including the Artemis campaign for lunar missions and preparation for future astronaut journeys to Mars.
Article by Mel Anara, based upon information from NASA News
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